C-17 epimers of deoxy-(O-8)-salinomycin from Streptomyces albus (ATCC 21838).
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منابع مشابه
Direct cloning and heterologous expression of the salinomycin biosynthetic gene cluster from Streptomyces albus DSM41398 in Streptomyces coelicolor A3(2)
Linear plus linear homologous recombination-mediated recombineering (LLHR) is ideal for obtaining natural product biosynthetic gene clusters from pre-digested bacterial genomic DNA in one or two steps of recombineering. The natural product salinomycin has a potent and selective activity against cancer stem cells and is therefore a potential anti-cancer drug. Herein, we separately isolated three...
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 30 7 شماره
صفحات -
تاریخ انتشار 1977